Genomics

Description

Course Description Contents: The course discusses the structure and function of genomes of organisms from all kingdoms. The topics that are treated cover: - chromosome structure and topology; - genome sequencing, genome assembly and functional annotation; - whole genome sequence analysis; genome synteny and evolution; - transcriptome analysis by RNA-seq; single-cell omics; epigenomics - functional genome analysis; - variation in genomes. Learning Outcomes: learning outcomes After successful completion of this course students are expected to be able to: Retrieve and describe information from genomic databases Describe genome analysis strategies related to genome assembly, annotation, and functional genomics Describe and explain organization, function and evolution of genomes Contrast features of genomes of different domains of life, and compare genomes of different species Apply and assess tools for genome analysis Interpret complex data and analysis results derived from complex biological systems Judge the merits of results and interpretations based on known strengths and weaknesses of data sources and analysis strategies Integrate results obtained from literature/research project Assumed Knowledge: Basic knowledge on molecular biology and genetics, such as given in GEN11806 Fundamentals in Genetics, or courses such as BIC10306 Practical Biological Chemistry or MOB20306 Gene Technology. Examination: Assessment method(s) Weighting (%) Minimum grade Validity* Group Assignment other 40 5,50 2 Literature/research project. If a student fail this assignment they can resubmit an improved assignment in the following period where the course is provided or in the resit period. Individual Written test with open questions 60 5,50 2 *The duration of the validity is expressed as years after the academic year in which a passing grade for this assessment was obtained. Literature: The contents of the computer exercises are available in Brightspace. Additional material in Brightspace consists of links to relevant websites, to the Powerpoint presentations of the lectures and to further background information in review papers. Literature for the research/literature project is accessible from literature databases and journal home pages. Practical information and Schedule Credits: 6 ECTS Language of Instruction: English Mode of Delivery: Taught on the Campus Campus Location: Wageningen Chair Group: Animal Breeding and Genomics Course Schedule: Link to the most recent course schedule Teaching Methods Below find the contact hours and teaching methods for this course. Teaching methods are expressed in credits study load (one credit equals 28 clock hours and study load includes alle necessary activities like preparation, contact hours and self study). Contact hours are expressed in time slots of 40 minutes. Teaching Methods: Contact hours:: 1 Credits:: 0,8; Contact hours:: 16 Credits:: 2,0; Contact hours:: 88 Credits:: 3,2 Grading of this course Grading scale: Grades (0-10) Course Periods Offered and Registration Below find in which period(s) the course is offered, how to register for this course and what course registration deadlines apply. For a complete overview, check our Academic Calender. Course has a limitation: This course has a limitation. Either is has a maximum number of participants and/or is an Academic Master Cluster course and/or is a Modular Skills Training Course. For courses with a maximum, students for which this course is a compulsory or restricted optional course, should register at least 1 week before the deadline mentioned to qualify for priority in being enrolled. Qualifying students up to the maximum will be enrolled in the course by the course coordinator. For Academic Master Cluster Courses and Modular Skills Training Courses, a specific registration procedure applies as outlined in this paragraph. Registration through OSIRIS Student: You can register through OSIRIS Student up to the deadline mentioned. Course Schedule: Link to the most recent course schedule Periods and deadlines for registration: Timeslot(s): Afternoon Registration Period: 1 June 2025 until 28 September 2025 23:59 Deregistration period: until 28 September 2025 23:59; Timeslot(s): Afternoon Registration Period: 1 June 2025 until 8 February 2026 23:59 Deregistration period: until 8 February 2026 23:59 Staff The course coordinator, examiner and lecturers of this course are mentioned below. When a special contact person or contact email address for this course applies, this is listed below the lecturers. When applicable, please use that way to contact the course team. Otherwise, contact the course coordinator to contact the course team. Staff: Email-address: marta.godia@wur.nl Email-address: martijn.derks@wur.nl; Email-address: marta.godia@wur.nl Email-address: martijn.derks@wur.nl Email-address: ole.madsen@wur.nl; Email-address: like.fokkens@wur.nl Email-address: marta.godia@wur.nl Email-address: martijn.derks@wur.nl Email-address: manu.gundappa@wur.nl Email-address: ole.madsen@wur.nl Email-address: hendrik-jan.megens@wur.nl Email-address: eric.schranz@wur.nl